Di-tri-octahedral smectite possesses the ability to bind C. difficile toxins A and B, C. perfringens enterotoxin and endotoxin in vivo while having no effect on bacterial growth or the action of metronidazole.

(Di-tri-octahedral Smectite min. 70%) GMP+ & FSA geborgd: Gebruiksaanwijzing: Gezonde pasgeboren veulens: Na een adequate inname van biest verstrek 1 volle maatschep (25 gram) DiaTox Absorber poeder, gemixt met 30 ml water, toedienen. Toedienen 6 uur nadat het veulen de eerste voeding van de merrie binnen heeft gekregen.

Smectite (Biosponge). Class of drug. Adsorbent, gastrointestinal protectant. Description Chemical name. Di-tri-octahedral smectite. Physical properties. A natural, hydrated aluminomagnesium silicate "clay".

Di tri octahedral smectite

However, treatment with Bio-sponge® paste, which is composed of a natural clay called Di-Tri-Octahedral Smectite, has been shown in several studies to be effective at adsorption of harmful toxins in the equine GI tract (4) and is what we use most often when treatment for foal heat diarrhea is … Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: results of a randomized clinical trial. Vet J. 2009; 182(2):210-4 (ISSN: 1532-2971) Biosponge: Di-tri-octahedral (DTO) smectite (clay minerals) is a natural hydrated aluminomagnesium silicate that binds to digestive mucus and increases resistance to bacterial damage by absorbing Article Unit Active component; Bio Sponge platinum: 9500 gr: Di-Tri-Octahedral Smectite: Equi-Sumo AP: 1000 ml: Ricebran oil, Herbs, Gamma-Orizanol: Quietex Paste Syringe Oral di-tri-octahedral smectite (Biosponge), 500 mg/kg BW, QID was administered for 3 d, and nasoesophageal feeding frequency was reduced. On days 3 and 4 of hospitalization diarrhea was still profuse and watery, and loperamide hydrochloride (Teva Pharmaceuticals USA, Sellerville, Pennsylvania, USA), 0.05 mg/kg BW, QID, PO was added to the treatment plan in an effort to decrease intestinal Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: Results of a randomized clinical trial more. by Diana Hassel a Sharon Spier. The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral Comprised of a natural clay, Di-Tri-Octahedral Smectite A negatively charged intestinal adsorbant designed to help support healthy intestinal function Widely used to support healthy gastrointestinal function in foals.Newborn foals: For best results, following an adequate intake of colostrum administer 30cc of Bio-Sponge® Paste 6 hours after the foal first nurses the mare. CONICET Digital, el repositorio institucional del CONICET, un servicio gratuito para acceder a la producción científico-tecnológica de investigadores, becarios y demás personal del CONICET. Which drugs to choose — POLYSORB or smectite For many years in every human body accumulate many harmful substances.

Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be treated with DTO smectite (n=37; 0.5 kg via nasogastric Abstract. The minerals of the montmorillonite group (smectites) can be distinguished from the vermiculites, as they are very similar to them in their thermal behaviour, as regards the temperatures of the exothermic peak. Preliminary studies using a model of lincomycin-induced colitis suggested that di-tri-octahedral (DTO) smectite, a natural clay material, may be useful for the treatment and prevention of colitis in horses ( Herthel, 2000 ).

Research performed in adult horses and foals, as well as through in vitro trials, indicates that Bio-Sponge® (Di-Tri Octahedral (DTO) smectite) is an effective tool for a variety of health concerns that result in diarrhea or gastrointestinal disturbances.

However, di-tri-octahedral smectite did not inhibit the growth of Clostridium difﬁcile and Clostridium perfringens, nor did it interfere with the activity of metronidazole." See: Di-tri-octahedral smectite (BiospongeTM) may help absorb luminal intestinal toxins. Nutritional support . Total or partial parenteral (TPN, PPN) nutrition should be considered in neonates.

The Effect of Smectite on the Corrosion of Iron Metal of cations and concluded that K+ fixation is different between di- and trioctahedral 2:1 clay minerals.

Probiotic therapy has been evaluated in humans with CDI. Results have been somewhat conflicting and equivocal, however, Conclusions and Clinical Relevance—Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies.

Administer twice daily for 6 days or as directed by your veterinarian. METHODS: Substances commonly used in equine practice (activated charcoal composition, di-tri-octahedral smectite, mineral oil and activated charcoal) were tested for their binding capacity for HGA using an in vitro incubation method. Di‐tri‐octahedral smectite is a type of clay that adsorbs C. difficile toxins in vitro, 28 and is commonly used in the treatment of CDI in horses. Probiotic therapy has been evaluated in humans with CDI. Results have been somewhat conflicting and equivocal, however, Conclusions and Clinical Relevance—Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies. Abstract. The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral (DTO) smectite product on clinical signs and prevalence of post-operative diarrhea in horses with colic associated with disease of the large intestine. Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be "Di-tri-octahedral smectite was effective in neutralizing Clostridium difﬁcile toxins A and B as well as Clostridium perfringens enterotoxin in vitro.
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60cc twice per day for an 1100lb horse, Bio Sponge contains only one ingredient - Di-Tri-Octahedral Smectite, a natural clay mineral according to Platinum Performance web site.

Keep dry. Conclusions and Clinical Relevance—Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies. Conclusions: Di‐tri‐octahedral smectite possesses the ability to bind C. difficile toxins A and B, C. perfringens enterotoxin and endotoxin in vivo while having no effect on bacterial growth or the action of metronidazole. Abstract.
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Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: results of a randomized clinical trial. Vet J. 2009; 182(2):210-4 (ISSN: 1532-2971)

The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral (DTO) smectite product on clinical signs and prevalence of post-operative diarrhea in horses with colic associated with disease of the large intestine. Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be Research performed in adult horses and foals, as well as through in vitro trials, indicates that Bio-Sponge® (Di-Tri Octahedral (DTO) smectite) is an effective tool for a variety of health concerns that result in diarrhea or gastrointestinal disturbances. Di-tri-octahedral smectite possesses the ability to bind C. difficile toxins A and B, C. perfringens enterotoxin and endotoxin in vivo while having no effect on bacterial growth or the action of metronidazole. Di-tri-octahedral smectite (generic name) DIGESTION Sold as Bio-Sponge. Digestion and Motility Drugs Abstract. The minerals of the montmorillonite group (smectites) can be distinguished from the vermiculites, as they are very similar to them in their thermal behaviour, as regards the temperatures of the exothermic peak.